In Baton Rouge, Lacey and Stacey restrain a patient suffering from violent hallucinations after overdosing on the synthetic drug Mojo. Meanwhile, Matt and Henry face the most difficult challenge paramedics encounter when an Austin man calls 911 to save his wife from cardiac arrest. And in Yonkers, New York, Alex and Jamal must determine what drug caused a woman to go unresponsive before her heart stops beating.