A man is arrested for killing his brother. But his defense attorney tries to turn medical evidence in his favor to get the alleged killer off on Florida's "Stand Your Ground" law.
New Orleans Detective Ryan Vaught investigates a gruesome and horrific murder: a grandmother and her four-year-old grandson shot in her bedroom, leaving the grandmother dead and the four-year-old struggling to survive.
In Tucson, a young man is found shot to death on the street. And in Memphis, Sergeant Debo Carson investigates the brutal murder of a woman whose body was found dumped on the railroad tracks.
In Birmingham, Detective Chris Anderson returns to his childhood neighborhood to investigate the murder of a man killed over ten pounds of marijuana.