An actress equally at home on stage, screen, and television, Dale has created a rich gallery of memorable characters in all three media. Among her numerous films awaiting release are White Bird in a Blizzard (with Shailene Woodley and Angela Basset), The Trials of Kate McCall (with Kate Beckinsale and Nick Nolte), Blues for Willadean (with Beth Grant and Octavia Spencer), San Patricos (with Beau Bridges and Kris Kristofferson), and this year's Sundance Festival hit C.O.G. Other feature films include Winter's Bone (for which she won the 2011 Independent Spirit Award for Best Supporting Actress), Iron Man 3, The Guilt Trip (with Barbra Streisand and Seth Rogen), and Being Flynn (with Robert DeNiro, Paul Dano and Julianne Moore).
She is familiar to television audiences for her recurring roles as Martha, the werewolf matriarch, on True Blood, and Patty "the daytime hooker" on My Name is Earl. She has also guest starred or recurred on such shows as Breaking Bad, Grey's Anatomy, Southland, Two Broke Girls, Weeds, Criminal Minds, CSI, Sordid Lives, Bones, The Closer, Ugly Betty, ER, Gilmore Girls, Frasier, and The X-Files.